EYE DISEASES
MACULAR DEGENERATION; RETINITIS PIGMENTOSA;
ISCHEMIC OPTIC NEURITIS
Patients with macular degeneration
have angiogenesis with abnormal vessels in the retina. The essential
feature is to restore normal photoreceptors and visual ability. The
goal is to stop retina degeneration and introduce healthy retina cells
into the subretina envirnonment that will form photoreceptors..
Stem cells that are pluripotent
can be transformed in the laboratory to retina progenitor cells. Patients
can now receive retina stem cells that are cultured with brain derived
neurotrophin factor, nerve growth factor and fibroblast growth factor
in the laboratory for four weeks. Retina precursor cells differentiate
into retina cells and photoreceptors. The retina stem cells and optic
neuron stem cells are implanted by an experienced ophthalmologist.
Prior to the procedure
and post procedure patients receive oral and injectable agents to stimulate
their own endogenous stem cells.
In addition prior to the
procedure patients will receive autologous stem cells from their own
bone marrow or peripheral blood.
Patients are followed by
retina examinations, retinogram, spatial acuity and luminescence threshold
to evaluate the treatment.